Quantification of endocytosis using a folate functionalized silica hollow nanoshell platform
نویسندگان
چکیده
منابع مشابه
Quantification of endocytosis using a folate functionalized silica hollow nanoshell platform.
A quantification method to measure endocytosis was designed to assess cellular uptake and specificity of a targeting nanoparticle platform. A simple N -hydroxysuccinimide ester conjugation technique to functionalize 100-nm hollow silica nanoshell particles with fluorescent reporter fluorescein isothiocyanate and folate or polyethylene glycol (PEG) was developed. Functionalized nanoshells were c...
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Hollow nanoshells of layered double hydroxide (LDH) have been fabricated using exfoliated LDH nanosheets as a shell building block and polystyrene beads as a sacrificial template.
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The development of synthetic process for hollow silica materials is an issue of considerable topical interest. While a number of chemical routes are available and are extensively used, the diameter of hollow silica often large than 50 nm. Here, we report on a facial route to synthesis ultrafine hollow silica nanoparticles (the diameter of ca. 24 nm) with high surface area by using cetyltrimethy...
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Gene therapy is a promising strategy for treatment of genetically caused diseases. Successful gene delivery requires an efficient carrier to transfer the desired gene into host cells. Recently, mesoporous silica nanoparticles (MSNs) functionalized with 25 kD polyethyleneimine (PEI) were extensively used as gene delivery carriers. However, 25 kD PEI could significantly reduce the safety of the m...
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Porous hollow spherical and rod-like silica nanoparticles were obtained via a surfactant templating method adopting hydroxyapatite (HAp) nanoparticles as an etchable core material.
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ژورنال
عنوان ژورنال: Journal of Biomedical Optics
سال: 2015
ISSN: 1083-3668
DOI: 10.1117/1.jbo.20.8.088003